N-acetylgalactosaminide α2-6 sialyltransferase 4

Abbreviation 

ST6GalNAcT-IV

Source

Human

Activity

Transfer Sia via an α2-6 linkage

Expression

&

Purification

Commercial Available 

Optimal Condition

37 °C

7.4

50 mM PBS (pH 7.4), 12 mM donor, 10 mM acceptor, incubate at 37 °C for 1 hour.

Temperature

pH

Metal ion:

Example condition:   

CMP-Neu5Ac

GalNAc

Donor:

Acceptor:

ST6GalNAcT-IV.png

Substrate Specificity

  • Wen, L.;  Liu, D.;  Zheng, Y.;  Huang, K.;  Cao, X.;  Song, J.; Wang, P. G., A One-Step Chemoenzymatic Labeling Strategy for Probing Sialylated Thomsen–Friedenreich Antigen. ACS Central Science 2018, 4 (4), 451-457.

References