Standard Protocols for Chemoenzymatic Synthesis of Glycoshpingolipids
The project is supported by NIH Common Fund Glycoscience Program U01GM120419.
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Santra A, Li Y, Yu H, Slack TJ, Wang PG, *Chen X. Highly efficient chemoenzymatic synthesis and facile purification of alpha-Gal pentasaccharyl ceramide Galα3nLc4βCer. Chem. Commun. 2017, 53, 8280-8283. PMID: 28695219.
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Yu H, Santra A, Li Y, McArthur JB, Ghosh T, Yang X, Wang PG, *Chen X. Streamlined chemoenzymatic total synthesis of prioritized ganglioside cancer antigens. Org. Biomol. Chem. 2018, 16, 4076-4080. PMID: 29789847.
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Santra A, *Yu H, *Chen X. Chapter 10. Synthesis of glycosphingolipids (GSLs). In Synthetic Glycomes. RSC Chemical Biology Book Series. Wang P. G., Guan W., Li L. Eds. 2019, pp. 226-253.
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†Yu H, †Gadi MR, Bai Y, Zhang L, Li L, Yin J, Wang PG, *Chen X. Chemoenzymatic total synthesis of GM3 gangliosides containing different sialic acid forms and various fatty acyl chains. J. Org. Chem. 2021, 86, 8672-8682. †These authors contributed equally. PMID: 34152144.